Best way to get from Ecuador to Germany

What is your advice?
Had been in Ecuador since Jan 2020, and now going back to Germany (am German).
What travel route would you recommend?
I would prefer to take just one direct flight, and do the rest via buses.
Thank you for your ideas.

Direct to Germany is not possible from Quito. The only non-stop flights I spotted at the moment were to Madrid, so unless you want to take ground transportation from Madrid to Germany I would recommend a one-stop flight instead. With one stop you can get to e.g. Munich or Frankfurt in February for just short of €900, then take local transport from there.

If you really only want to take one flight, you could travel overland to Bogotá and take a direct Lufthansa flight from there to Frankfurt. But it will be more expensive at around €1,200.